PGA & HA: Hoʻonui Synergistic, E ʻōlelo aloha i ka Stickiness, Moisturizing a me Antioxidant Duet

#Hoʻolauna

Sodium polyglutamate (PGA)he polymer hiki ke hoʻoheheʻe ʻia i ka wai i hana ʻia efermentation microbial.Hoʻohana nui ʻia ia mamālama ʻilihuahana anā mea hoʻonaninanima muli o kāna mau waiwai moisturizing maikaʻi a me nā waiwai multifunctional.E hōʻike ana kēia ʻatikala i ke kumu, ka hoʻolālā kemika, nā ʻano a me ka hoʻohana ʻana oka sodium polyglutamatei nā huahana mālama ʻili i nā kikoʻī.

#Source and Chemical Structure

ʻO ka sodium polyglutamateua ʻike mua ʻia ma ka natto, kahi meaʻai Kepani kuʻuna.ʻO ke siliki viscous loa i ka nattoPGA.Hoʻopili ʻia kēia mea mai ka waika glutamic kūlohelohe a degradable a hana ʻia e ka fermentation o Bacillus subtilis.ʻO Bacillus subtilis kahi mea hoʻohui microbial additive (GRAS) i ʻike ʻia ma ka honua, i loaʻa maoli a palekana no ke kino kanaka.

ʻO ke kumu kumu oPGAhe 5000-10000 glutamic acid mole i polymerized ma oγ- nā paʻa amide.Aia i loko o ka mole ka nui o nā pūʻulu polar e like me ka hydroxyl a me nā hui carboxyl, hiki ke hana i nā paʻa hydrogen i loko a ma waena o nā mole, a laila e hoʻopaʻa ai i ka nui o ka wai a hoʻomaikaʻi nui i kona hopena moisturizing.

#Nā hiʻohiʻona a me ka hopena

1. **Hana maikaʻi i ka moisturizing**: Hiki i ka PGA ke komo a laka i ka nui o ka wai, e hoʻomaikaʻi nui i ka hydration o ka ʻili.Ke hoʻohana ʻia mesodium hyaluronate (HA), hiki iā ia ke hoʻolōʻihi i ka manawa moisturizing o HA, e hoʻemi i kona paʻa, a e hoʻomāhuahua i ka ʻili a me ka maʻalahi.

2. **Ka hana antioxidant**: Loaʻa i ka PGA ka hana antioxidant, hiki ke ʻoki i nā radical manuahi, a pale i ka ʻili mai ka pōʻino oxidative.Ua hōʻike ʻia nā haʻawina ʻoi aku ka maikaʻi o ka PGA me ke kaumaha molekala o 1.4 miliona Da ma mua o ka PGA me ka paona molekala o 1 miliona Da i ka hoʻopaʻa ʻana i nā radical manuahi DPPH.

3. **E hoʻonui i ka ʻike o ka moisturizing factor (NMF) i loko o ka ʻili**: Hiki i ka PGA ke hoʻoikaika i ka hanauna o NMF i ka ʻili, hoʻonui i ka hiki ke hoʻomaʻemaʻe i ka ʻili, a loaʻa i ka hopena o ka meaʻai hohonu.

4. **Keʻokeʻo a me ka anti-ʻelemakule**: Hiki i ka PGA ke hoʻomalu mālie i ka hana o tyrosinase, hoʻopaneʻe i ka hoʻokumu ʻana o nā kiko, a ma ka manawa like e hoʻomaikaʻi i ka paʻa o HA i ka ʻili, hoʻonui i ka ʻike HA, a loaʻa i ka hopena o ka whitening a me ka anti-aging.

# Kaumaha Molecular a me ka noi

Wahi a ke kaumaha mole, hiki ke hoʻokaʻawale ʻia ka PGA i ʻekolu mau ʻano: ke kaumaha mole kiʻekiʻe, ke kaumaha molecular medium a me ke kaumaha molecular haʻahaʻa, kēlā me kēia me nā ʻano like ʻole a me nā noi.

- **PGA-HMW (ke kaumaha molekala kiʻekiʻe, >700kDa)**: hoʻomaʻamaʻa lōʻihi, hana i kahi kiʻiʻoniʻoni ma ka ʻili o ka ʻili, hoʻomaikaʻi nui i ka hopena moisturizing.

- **PGA-LMW (kaumaha molekala waena, 70-150kDa)**: hoʻomaʻemaʻe a keʻokeʻo, hoʻomaikaʻi i ka ʻili a me ka elasticity.

- **PGA-Oligo (ke kaumaha molekala haʻahaʻa, <10kDa)**: meaʻai hohonu, hiki pololei i ka papa basal, hoʻoikaika i ka hana NMF a me ka absorption o nā meaʻai.

# Noi a hoʻohana i nā manaʻo

He kūpono ʻo PGA no ka moisturizing, anti-aging a me nā huahana keʻokeʻo, me ka manaʻo ʻia o0.1% a 1%.Pono e hoʻohana ʻia nā emulsifiers anti-ionic e like me ka hiki i ke ʻano e hoʻonui i ka hopena o ka PGA.

#Hoʻoholo

Ma ke ʻano he biopolymer kūlohelohe, palekana a maikaʻi hoʻi,ka sodium polyglutamate (PGA)hōʻike i ka hiki ke hoʻohana nui i nā huahana mālama ʻili a me nā mea hoʻonaninani.ʻO kāna mau waiwai moisturizing maikaʻi loa, ka hana antioxidant a me nā pono he nui i ke olakino ʻili e lilo ia i mea koʻikoʻi i nā huahana mālama ʻili hou.Me ka hohonu o ka noiʻi a me ka holomua o ka ʻenehana noiʻi,PGAua manaʻo ʻia e pāʻani i kahi kuleana koʻikoʻi i nā kula hou aʻe a lawe mai i nā mea hou a me ka hoʻomohala ʻana i ka ʻenehana mālama ʻili.